![]() The pleural efusion pH was 7.35 (normal, 6.8-7.6), proteins were 32 g/l (normal, 0-30), and lactate dehydrogenase, adenosine deaminase and carcinoembryonic antigen levels were 2186 U/l (normal, 0-200), F30 U/l (normal, 0-40) and 1.64 ng/ml (normal, 0-6.5), respectively. The pleural puncture technique was applied to drain excessive fuid, and Rivalta test results were positive. Ultrasonography of the upper abdomen and uterus did not reveal any anomaly.Ĭomputed tomography of the chest, revealing slight swelling of the mediastinal lymph nodes and a small amount of bilateral pleural effusion, with slightly more on the right side than on the left. Ultrasonography of the neck revealed multiple swollen bilateral supraclavicular lymph nodes, with some as large as 16 × 7 mm. Bone marrow cytological analysis revealed bone marrow hyperplasia.Ĭomputed tomography (CT) of the chest revealed slight swelling of the mediastinal lymph nodes and a small amount of bilateral pleural effusion, which was slightly more severe on the right side ( Figure 1). The T-SPOT and purifed protein derivative tests for tuberculosis were negative, as were tests for pleural tuberculosis antibodies. The results for tumor markers, autoimmune antibodies, anti-neutrophil cytoplasmic antibodies and blood cultures were normal. Laboratory examinations revealed the following: white blood cell count, 2.45 × 10 9/l neutrophils: 48.70% lymphocytes: 42% red blood cell count: 3.9 × 10 12/l hemoglobin: 101 g/l platelets: 141 × 10 9/l erythrocyte sedimentation rate: 30 mm/h procalcitonin: 0.095 ng/ml and C-reactive protein: 19.11 mg/I. Double lung auscultation detected lower breathing sounds. ![]() Physical examination on admission revealed that both cervical lymph nodes were swollen and tender, more obviously so on the lef side. Then days before admission, the patient began to experience intermittent chills and a fever between 38.5 and 40 ☌. CASE REPORTĪ 26-year-old woman was hospitalized due to anorexia and fatigue that had lasted one month. Here, we report a case in which the patient experienced unexplained fever, swelling of the cervical lymph node and bilateral pleural effusion and was ultimately diagnosed with HNL based on the results from a lymph node biopsy. However, pleural effusion has rarely been reported in HNL patients. Histiocytic necrotizing lymphadenitis (Kikuchi-Fujimoto disease) associated with antiphospholipid syndrome: case report and literature review. Papaioannou G, Speletas M, Kaloutsi V, Pavlitou-Tsiontsi A. Systemic lupus erythematosus with simultaneous onset of Kikuchi-Fujimoto’s disease complicated with antiphospholipid antibody syndrome: a case report and review of the literature. There have been reports of co-occurrence of HNL with other diseases, including systemic lupus erythematosus (SLE), hemophagocytic syndrome and antiphospholipid syndrome. ![]() ![]() Some scholars believe that HNL is not an independent disease and that it may be a manifestation of an underlying autoimmune disorder as such, the diagnosis and treatment for HNL should be targeted to the underlying disease instead. Histiocytic necrotizing lymphadenitis (HNL) is a rare disorder, and its pathogenesis remains unclear. Histiocytic necrotizing lymphadenitis Pleural effusion Tuberculosis Lymph nodes Biopsy We presented this case to improve diagnostic awareness of this condition among clinicians and help reduce the likelihood of misdiagnosis. The pathogenesis of HNL remains unclear, and pleural effusion is rarely reported in HNL patients. After treatment with glucocorticoid, the patient regained normal body temperature, the swelling of the lymph nodes disappeared and the pleural effusion was reabsorbed. Here, we report a case in which a patient experienced unexplained fever, swelling of the cervical lymph node and bilateral pleural effusion and was ultimately diagnosed with HNL based on results from a lymph node biopsy. There have been reports of co-occurrence of HNL with other diseases, including systemic lupus erythematosus, hemophagocytic syndrome and antiphospholipid syndrome. Histiocytic necrotizing lymphadenitis (HNL) is a rare disorder that is often benign and self-limiting.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |